Gene Therapy

Findings from Washington University, Medical Department broaden understanding of gene therapy

Published in Gene Therapy Weekly, October 30th, 2008

According to recent research published in the journal Stem Cells, "Adult tissue stem cells (SCs) share functional properties regardless of their tissue of residence. It had been thought that SCs might also share expression of certain ''stemness'' genes, although early investigations for such genes were unsuccessful."

"Here, we show that SCs from diverse tissues do preferentially express certain types of genes and that SCs resemble other SCs in terms of global gene expression more than they resemble the differentiated cells (DCs) of the tissues that they supply. Genes associated with nuclear function and RNA binding were over-represented in SCs. In contrast, DCs...

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Source: Gene Therapy Weekly (2008-10-30)

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