Life Sciences
Scientists at University of Iowa, Department of Pharmacology describe research in life sciences
Published in Gene Therapy Weekly, November 6th, 2008
A report, 'Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells,' is newly published data in Cellular Signalling. "Recent studies showed that Fyn is a mediator of the LHR-induced activation of the ERK1/2 cascade in MA-10 cells. Since the LHR is a G protein-coupled receptor and the Src family of kinases can be activated by some Galpha subunits and by the non-visual arrestins we investigated the role of these signaling molecules in the LHR-provoked activation of Fyn," scientists in the United States report.
"Small interfering RNAs (siRNAs) that target two Galpha subunits that participate in LHR signaling...
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Source: Gene Therapy Weekly (2008-11-06)
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