Published in Gene Therapy Weekly, November 6th, 2008
"The mechanisms behind its antiangiogenic effects are not well characterized. To determine which nuclear factor, if any, may be involved in the antiangiogenic effects of CyA, we performed a microarray analysis of human aortic endothelial cells (HAEC) subjected to CyA and another calcineurin inhibitor, FK 506. HAEC were divided into four groups: (1) HAEC incubated with CyA 2 mu g/mL; (2) HAEC incubated with CyA 10 mu g/mL; (3)...
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