Vector Development
Study data from K.L. Douglas et al provide new insights into vector development
Published in Gene Therapy Weekly, November 6th, 2008
"Problems related to the safety and efficacy of gene therapies have checked the enthusiasm once surrounding this field, though it remains a promising approach for the treatment of numerous diseases. Despite the high transfection efficiencies attainable using viral vectors, manufacturing difficulties. safety concerns, and limitations related to targeting and plasmid size have prompted considerable research into the development of non-viral vectors," scientists in Canada report.
"Non-viral vectors demonstrate low toxicity, low, immunogenicity, and ease of manufacture. However, they have not yet achieved the transfection efficiencies displayed by viruses. The inability to...
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Source: Gene Therapy Weekly (2008-11-06)
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