Gene Therapy

Research reports from University of California provide new insights into gene therapy

Published in Gene Therapy Weekly, November 13th, 2008

"Testis-specific protein Y-encoded (TSPY) is the putative gene for the gonacloblastoma locus on the Y chromosome. TSPY is expressed in normal germ cells of fetal and adult testis and ectopically in tumor germ cells, including gonadoblastoma in intersex patients, testicular germ cell tumors, prostate cancer and other somatic cancers," investigators in the United States report.

"It is a member of the TSPY/SET/NAP1 superfamily and harbors a highly conserved domain, termed SET/NAP domain. To explore its possible role(s) in tumorigenesis, we had performed a yeast two-hybrid screen of a fetal gonadal cDNA library and identified the translation elongation factor eEF1A as a...

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Source: Gene Therapy Weekly (2008-11-13)

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