Cancer Gene Therapy
New findings from Hirosaki University in the area of cancer gene therapy described
Published in Gene Therapy Weekly, December 4th, 2008
Investigators publish new data in the report 'Claudin-1 expression is induced by tumor necrosis factor-alpha in human pancreatic cancer cells.' "Claudin-1 is a membrane protein with four transmembrane domains, that is exclusively localized at cellular tight junctions. Recent studies have reported that claudin-1 plays an important role in cancer invasion and metastasis," scientists writing in the International Journal of Molecular Medicine report.
"However, the significance of claudin-1 in pancreatic cancer is still unknown. In the present study, we investigated the role of claudin-1 expression in pancreatic cancer growth using the PANC-1 human pancreatic cancer...
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Source: Gene Therapy Weekly (2008-12-04)
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