Non-Small Cell Lung Cancer

New findings from G. Bepler and co-authors describe advances in non-small cell lung cancer

Published in Gene Therapy Weekly, December 11th, 2008

"A trial of neoadjuvant gemcitabine and pemetrexed (GP) chemotherapy in patients with resectable non-small cell lung cancer was conducted. The goal was to achieve a disease response rate of 50% and to determine if the expression levels of genes associated with GP metabolism are predictive of response," scientists in the United States report.

"Patients had staging with a computed tomography scan, whole body F-18 fluorodeoxyglucose positron emission tomography, and mediastinoscopy. Four biweekly cycles of GP were given. Patients were restaged, and those with resectable stage IB-III disease had thoracotomy. Fresh frozen tumor specimens were collected before and after...

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Source: Gene Therapy Weekly (2008-12-11)

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