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Ductal Carcinoma in Situ
Reports summarize ductal carcinoma in situ research from Shandong University
December 18th, 2008
" WWOX and FHIT are two candidate tumor suppressor genes located inactive fragile sites, the damage of which has been associated with the development of breast cancer. The association of the expression of these genes and the development of breast cancer has not been fully explored," scientists in Jinan, People's Republic of China report. "We evaluated mRNA and protein expression of WWOX and FHIT in breast tissue with normal histological appearances, atypical ductal hyperplasia, ductal carcinoma in situ, and invasive cancer to see if a progressive decline in expression was present. Reverse transcription-polymerase chain reaction and Western blotting were used to...
Source: Gene Therapy Weekly (2008-12-18)
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