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Enzyme Research
Researchers at University of Quebec release new data on enzyme research
December 18th, 2008
According to recent research published in the American Journal of Physiology - Endocrinology and Metabolism, "Fatty acid synthase (FAS) is a key enzyme of hepatic lipogenesis responsible for the synthesis of long-chain saturated fatty acids. This enzyme is mainly regulated at the transcriptional level by nutrients and hormones." "In particular, glucose, insulin, and T-3 increase FAS activity, whereas glucagon and saturated and polyunsaturated fatty acids decrease it. In the present study we show that, in liver, T-3 and insulin were able to activate FAS enzymatic activity, mRNA expression, and gene transcription. We localized the T-3 response element (TRE) that...
Source: Gene Therapy Weekly (2008-12-18)
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