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Gene Therapy



Research from University of Sao Paulo yields new findings on gene therapy



December 18th, 2008

According to recent research published in the Canadian Journal of Microbiology, "To identify genes differentially expressed in a strain of the mold Aspergillus nidulans carrying a loss-of-function mutation in palA, a gene in the pH-responsive signal transduction pathway, suppression subtractive hybridization was performed between RNA isolated from the biA1 and biA1 palA1 strains grown under limiting inorganic phosphate at pH 5.0."

"We have identified several genes upregulated in the biA1 palA1 mutant strain that play important roles in mitotic fidelity, stress responses, enzyme secretion, signal transduction mechanisms, development, genome stability, phosphate...


Source: Gene Therapy Weekly (2008-12-18)

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