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Gene Therapy Weekly

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Gene Therapy



Research on gene therapy published by L.Z. Chen et al



December 18th, 2008

"We previously demonstrated that allopolyploidization could induce phenotypic variations and genome changes in a newly synthesized allotetraploid in Cucumis. To explore the molecular involvement of epigenetic phenomena, we investigated cytosine methylation in Cucumis by using methylation-sensitive amplified polymorphism (MSAP)," scientists in Nanjing, People's Republic of China report.

"Results revealed a twofold difference in the level of cytosine methylation between the reciprocal F-1 hybrids and the allotetraploid. Analysis of the methylation pattern indicated that methylation changed at 2.0% to 6.4% of total sites in both the F-1 hybrids and the allotetraploid...


Source: Gene Therapy Weekly (2008-12-18)

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