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Gene Therapy
Research results from University of Minnesota update knowledge of gene therapy
December 18th, 2008
According to recent research from the United States, "Small interfering RNAs (siRNAs) have become an indispensable tool for the investigation of gene functions." "Most existing siRNA design tools were trained on datasets assembled from confined origins, incompatible with the diverse siRNA laboratory practice to which these tools will ultimately be applied. We have performed an updated analysis using the disjunctive rule merging (DRM) approach on a large and diverse dataset compiled from siRecords, and implemented the resulting rule sets in siDRM, a new online siRNA design tool. siDRM also implements a few high-sensitivity rule sets and fast rule sets, links to...
Source: Gene Therapy Weekly (2008-12-18)
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