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Gene Therapy
Researchers at Aarhus University have published new data on gene therapy
December 18th, 2008
"Although the biophysical fingerprints (ion selectivity, voltage- dependence, kinetics, etc) of Ca2+-activated Cl- currents are well established, their molecular identity is still controversial. Several molecular candidates have been suggested; however, none of them has been fully accepted," researchers in Aarhus, Denmark report. "We have recently characterized a cGMP- dependent Ca2+-activated Cl- current with unique characteristics in smooth muscle cells. This novel current has been shown to coexist with a ''classic'' (cGMP- independent) Ca2+-activated Cl- current and to have characteristics distinct from those previously known for Ca2+-activated Cl- currents. Here, we...
Source: Gene Therapy Weekly (2008-12-18)
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