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Life Sciences
Studies conducted at University of Bern on life sciences recently published
December 18th, 2008
"Cation/proton exchange has been recognized for decades in mammalian mitochondria, but the exchanger proteins have eluded identification. In this study, a cDNA from a human brain library, previously designated NHA2 in the genome, was cloned and characterized," scientists writing in the Journal of the American Society of Nephrology report. "The NHA2 transcript bears more similarity to prokaryotic than known eukaryotic sodium/proton exchangers, but it was found to be expressed in multiple mammalian organs and cultured cells. A mAb to NHA2 was generated and found to label an approximately 55-kD native protein in multiple tissues and cell lines. The specificity of...
Source: Gene Therapy Weekly (2008-12-18)
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