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Studies from University of California add new findings in the area of gene therapy

Published in Gene Therapy Weekly, January 1st, 2009

Scientists discuss in 'HRASLS3 is a PPARgamma-selective target gene that promotes adipocyte differentiation' new findings in gene therapy. According to recent research from the United States, "The prevalence of obesity and its associated metabolic diseases worldwide has focused attention on understanding the mechanisms underlying adipogenesis. The nuclear receptor PPARgamma has emerged as a central regulator of adipose tissue function and formation."

"Despite the identification of numerous PPARgamma targets involved in a range of processes, from lipid droplet formation to adipokine secretion, information is still lacking on targets downstream of PPARgamma that directly...

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