Proteomics
Reports outline proteomics study findings from A. Matsushika and colleagues
Published in Gene Therapy Weekly, January 1st, 2009
"A recombinant Saccharomyces cerevisiae strain transformed with xylose reductase (XR) and xylitol dehydrogenase (XDH) genes from Pichia stipitis has the ability to convert xylose to ethanol together with the unfavorable excretion of xylitol, which may be due to cofactor imbalance between NADPH-preferring XR and NAD+-dependent XDH. To reduce xylitol formation, we have already generated several XDH mutants with a reversal of coenzyme specificity toward NADP+," scientists writing in the journal Applied Microbiology and Biotechnology report.
"In this study, we constructed a set of recombinant S. cerevisiae strains with xylose-fermenting ability, including...
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Source: Gene Therapy Weekly (2009-01-01)
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