Published in Gene Therapy Weekly, January 8th, 2009
"Although IL-17F is considered to be a weak IL-17A analog that is also mediating its effect via IL-17R, its exact role and in vivo functions are unknown. Our goal was to determine the in vivo activity of IL-17F on granulopoiesis as well as on release of granulopoiesis-stimulating downstream cytokines in mice and directly compare its effect to IL-17A. Murine IL-17A (mIL-17A) or IL-17F (mIL-17F) was...
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