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Cystic Cancer Genetics

Researchers at College of Medicine target cystic cancer genetics

Published in Gene Therapy Weekly, January 8th, 2009

Data detailed in 'Relations among expression of CXCR4, histological patterns, and metastatic potential in adenoid cystic carcinoma of the head and neck' have been presented. According to recent research published in the International Journal of Oncology, "Adenoid cystic carcinoma (ACC) may acquire a chemokine-mediated mechanism during the process of metastasis. To investigate the involvement of chemokines in metastasis from ACC, expression of CXCR4 in surgical specimens of ACC and two tumor lines transplantable to nude mice was examined immunohistochemically."

"In addition, the expression levels of CXCR4 protein and mRNA were examined by Western blotting and...

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