Gene Therapy
Recent findings from University of Oxford highlight research in gene therapy
Published in Gene Therapy Weekly, January 15th, 2009
According to recent research from Oxford, the United Kingdom, "Type IV secretion systems (T4SSs) are multisubunit cell-envelope-spanning structures, ancestrally related to bacterial conjugation machines, which transfer proteins and nucleoprotein complexes across membranes. T4SSs mediate horizontal gene transfer, thus contributing to genome plasticity and the evolution of pathogens through dissemination of antibiotic resistance and virulence genes."
"Moreover, T4SSs are also used for the delivery of bacterial effector proteins across the bacterial membrane and the plasmatic membrane of eukaryotic host cell, thus contributing directly to pathogenicity. T4SSs are usually...
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Source: Gene Therapy Weekly (2009-01-15)
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