Published in Gene Therapy Weekly, February 5th, 2009
"These transcripts, named BRCA1-PI21-Delta 2-21 and BRCA1-Delta 2-14, lacked most exons of full length BRCA1 gene, but maintained the original reading frame. We also demonstrated the presence of BRCA1-PI21-Delta 2-21 in several human cell lines. Expression of both variants fused with green fluorescent protein (GFP) showed that they targeted different subcellular compartments in the transfected...
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