Liposomes
Study data from Rutgers University update knowledge of liposomes
Published in Gene Therapy Weekly, February 12th, 2009
In this recently published article, scientists in the United States conducted a study "To develop a novel nanomedicine approach for the treatment of multidrug-resistant (MDR) cancer by combining an anticancer drug and suppressors of cellular resistance within one multifunctional nanocarrier-based delivery system (NDS). The NDS consisted of cationic liposomes (carrier, 100-140 nm), doxorubicin (DOX, anticancer drug), siRNA targeted to MRP1 and BCL2 mRNA (suppressors of pump and nonpump cellular-resistance, respectively)."
"The resulting approximately 500 nm complex has a zeta potential of +4 mV. The NDS provides an effective co-delivery of DOX and siRNA as well as...
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Source: Gene Therapy Weekly (2009-02-12)
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