Antisense Technology
Research on antisense technology published by K. Oszajca et al
Published in Gene Therapy Weekly, February 19th, 2009
"In this study we examined the effects of exogenous nitric oxide (sodium nitroprusside, SNP) and hydrogen peroxide (H2O2) on the expression level of tissue-type plasminogen activator (t-PA), urokinase-type plasminogen activator (u-PA), urokinase-type plasminogen activator receptor (u-PAR), and plasminogen activator inhibitor type 1 (PAI-1) in human umbilical vein endothelial cells (HUVEC). The expression of selected genes involved in fibrynolysis under the influence of oxidative stress was analyzed at the levels of mRNA, protein, and promoter activity," scientists in Lodz, Poland report.
"The results of the conducted studies revealed that oxidative stress in endothelial...
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Source: Gene Therapy Weekly (2009-02-19)
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