B-Cell Lymphoma

Research from G.H. Wang and colleagues has provided new data on B-cell lymphoma

Published in Gene Therapy Weekly, February 19th, 2009

According to recent research from the United States, "Gastric extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MZL-MALT) is speculated to be immune mediated and is notable for responding to treatment by Helicobacter pylori eradication. However, the gastric MZL-MALT with t(11;18)(q21;q21) has been shown to be resistant to treatment by H. pylori eradication."

"We studied the molecular, immunohistochemical, and histological aspects of 48 cases of gastric MZL-MALT and used a reverse transcription real-time PCR assay to assess the presence of a t(11; 18)(q21;q21) in formalin-fixed, paraffin-embedded tissue. Florescence in situ hybridization for...

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Source: Gene Therapy Weekly (2009-02-19)

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