Adenoid Cystic Cancer
Researchers at Hirosaki University, Medical Department have published new data on adenoid cystic cancer
Published in Gene Therapy Weekly, March 12th, 2009
According to recent research from Hirosaki, Japan, "Thymidylate synthase (TS) is an important target for chemotherapeutic treatment of cancer and high expression of TS has been associated with poor prognosis or refractory disease in several cancers including colorectal and head and neck cancer. Although TS is known to regulate cell cycles and transcription factors, its potency as a therapeutic target has not been fully explored in adenoid cystic carcinoma (ACC)."
"An ACC cell line (ACC3) was transfected with siRNA targeting the TS gene and inhibition of cell growth and induction of apoptosis-associated molecules were evaluated in vitro. In addition, the in vivo effect...
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Source: Gene Therapy Weekly (2009-03-12)
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