Published in Gene Therapy Weekly, March 12th, 2009
"Our vectors are deleted for the essential immediate early genes ICP4 and ICP27. These genes are controlled by unique promoters having enhancer elements responsive to a viral structural protein VP16. The expression of these genes occurs prior to the activation of all other lytic functions and is thus required to initiate and complete the...
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Source: Gene Therapy Weekly (2009-03-12)
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