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Cancer Gene Therapy

University of Alabama, Department of Biology publishes research in cancer gene therapy

Published in Gene Therapy Weekly, March 19th, 2009

Research findings, 'Strategies targeting telomerase inhibition,' are discussed in a new report. According to a study from the United States, "Telomerase plays a pivotal role in cellular immortality and tumorigenesis. Its activity is normally not detectable in most somatic cells while it is reactivated in the vast majority of cancer cells."

"Therefore, inhibition of telomerase has been viewed as a promising anticancer approach due to its specificity for cancer cells. Studies so far have shown that telomerase inhibition can inhibit the proliferation of cancer cells or cause apoptosis while it has no effect on most normal cells. Strategies currently being applied to induce...

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