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Gene Therapy

Data on gene therapy detailed by W. Zhang and co-authors

Published in Gene Therapy Weekly, March 26th, 2009

According to recent research published in the journal Human Genetics, "In addition to the differences between populations in transcriptional and translational regulation of genes, alternative pre-mRNA splicing (AS) is also likely to play an important role in regulating gene expression and generating variation in mRNA and protein isoforms. Recently, the genetic contribution to transcript isoform variation has been reported in individuals of recent European descent."

"We report here results of an investigation of the differences in AS patterns between human populations. AS patterns in 176 HapMap lymphoblastoid cell lines derived from individuals of European and...

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