DNA Research
New DNA research reported from Institute of Biomedical Science
Published in Gene Therapy Weekly, March 26th, 2009
Investigators publish new data in the report 'The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1.' According to recent research from Taipei, Taiwan, "Cell cycle progression is monitored constantly to ensure faithful passage of genetic codes and genome stability. We have demonstrated previously that, upon DNA damage, TTK/hMps1 activates the checkpoint kinase CHK2 by phosphorylating CHK2 at Thr68."
"However, it remains to be determined whether and how TTK/hMps1 responds to DNA damage. In this report, we present evidence that TTK/hMps1 can be induced by DNA damage in normal human fibroblasts. Interestingly, the induction depends on...
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Source: Gene Therapy Weekly (2009-03-26)
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