Gene Therapy
Researchers from Max Planck Institute for Developmental Biology, Department of Molecular Biology publish new studies and findings in the area of gene therapy
Published in Gene Therapy Weekly, March 26th, 2009
Scientists discuss in 'Triggering the formation of tasiRNAs in Arabidopsis thaliana: the role of microRNA miR173' new findings in gene therapy. According to a study from Tubingen, Germany, "Trans-acting small interfering RNAs (tasiRNAs) comprise a class of endogenous small RNAs that are generated from TAS gene-derived transcripts after these are cleaved at a microRNA (miRNA) target site. Arabidopsis thaliana has four families of TAS genes: miR173 triggers tasiRNA production from TAS1 and TAS2, miR390 from TAS3 and miR828 from TAS4."
"The two-hit trigger model postulates that dual target sites in the same transcript are often sufficient to initiate tasiRNA production,...
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Source: Gene Therapy Weekly (2009-03-26)
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