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Researchers from University Nacional Autonoma of Mexico, Department of Molecular Microbiology discuss findings in gene therapy

Published in Gene Therapy Weekly, March 26th, 2009

Investigators publish new data in the report 'Biochemical features and functional implications of the RNA-based T-box regulatory mechanism.' "The T-box mechanism is a common regulatory strategy used for modulating the expression of genes of amino acid metabolism-related operons in gram-positive bacteria, especially members of the Firmicutes. T-box regulation is usually based on a transcription attenuation mechanism in which an interaction between a specific uncharged tRNA and the 5' region of the transcript stabilizes an antiterminator structure in preference to a terminator structure, thereby preventing transcription termination," researchers in Cuernavaca, Mexico report.

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