Life Sciences
New life sciences research from University of Tubingen described
Published in Gene Therapy Weekly, March 26th, 2009
Current study results from the report, 'Post-transcriptional regulation of adapter molecules by IL-10 inhibits TLR-mediated activation of antigen-presenting cells,' have been published. According to a study from Tubingen, Germany, "Toll-like receptors (TLRs) act to sense the environment for microbial products and submit danger signals to antigen-presenting cells (APCs) resulting in activation of complex immune responses. In this study, we analyzed the function of human monocyte-derived APCs generated in vitro in the presence of interleukin (IL)-10 upon activation by TLR ligands."
"Exposure of these APCs to IL-10 resulted in a skewed phenotypic maturation in response to...
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Source: Gene Therapy Weekly (2009-03-26)
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