Antisense Technology
Scientists at Yale University target antisense technology
Published in Gene Therapy Weekly, March 26th, 2009
"We report here that two mills, miR-210 and miR-373, are up-regulated in a hypoxia-inducible factor-la-dependent manner in hypoxic cells. Bioinformatics analyses suggested that these mills could regulate factors implicated in DNA repair pathways. Forced expression of miR-210 was found to suppress the levels of RAD52, which is a key factor in homology-dependent repair (HDR); the forced expression of miR-373...
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Source: Gene Therapy Weekly (2009-03-26)
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