Published in Gene Therapy Weekly, April 2nd, 2009
"Dystrophin gene multiplex polymerase chain reaction and multiplex ligation-dependant probe amplification analysis showed that both males carried an in-frame deletion of exons 45-55. Segregation analysis revealed two additional asymptomatic boys in this family," wrote V. Ferreiro and colleagues, University of Buenos Aires.
The researchers concluded: "Our finding supports previous predictions that exons 45-55 are the optimal multiexon skipping target in antisense gene...
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