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Ovarian Cancer

Findings in theoretical biology reported from University of Rochester

Published in Gene Therapy Weekly, April 9th, 2009

According to recent research published in the Journal of Theoretical Biology, "Recent years have seen an unprecedented surge of research activity in studies of gene expression. This extensive work, however, has been almost uniformly focused on genome-wide gene expression and has largely ignored the fundamental fact that every gene has a specific chromosome location."

"We propose a novel method of spectral analysis for detecting hidden periodicities in gene expression signals ordered along the length of each chromosome. Using this method, we have discovered that each chromosome in rodents and humans has a unique periodic pattern of gene expression. The uncovered...

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