Published in Gene Therapy Weekly, April 16th, 2009
"Besides its protection against ischaemia-reperfusion injury and nephritis in mice, we previously reported that TMP reverses gentamicin-induced apoptosis in rat kidneys. Haem oxygenase-1 (HO-1) induction by TMP has also been shown to attenuate myocardial ischaemia/reperfusion injury in rats. We used rat renal tubular (NRK-52E) cells, transformed cells with HO-1 overexpression or knockdown, and an...
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