HIV/AIDS
Studies from University of California further understanding of HIV/AIDS
Published in Gene Therapy Weekly, April 23rd, 2009
"Gene transfer has potential as a once-only treatment that reduces viral load, preserves the immune system and avoids lifetime highly active antiretroviral therapy. This study, which is to our knowledge the first randomized, double-blind, placebo-controlled, phase 2 cell-delivered gene transfer clinical trial, was conducted in 74 HIV-1-infected adults who received a tat-vpr-specific anti-HIV ribozyme (OZ1) or placebo delivered in autologous CD34(+) hematopoietic progenitor cells," researchers in the United States report.
"There were no OZ1-related adverse events. There was no statistically significant difference in viral load between the OZ1 and placebo group at the...
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Source: Gene Therapy Weekly (2009-04-23)
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