Alcoholism

Findings from University of Louisville broaden understanding of alcoholism

Published in Gene Therapy Weekly, April 23rd, 2009

"Steatosis is a critical stage in the pathology of alcoholic liver disease (ALD), and preventing steatosis could Protect against later stages of ALD. PKC epsilon has been shown to Contribute to hepatic steatosis in experimental non-alcoholic fatty liver disease (NAFLD); however, the role of PKC epsilon. in ethanol-induced steatosis has not been determined," researchers in the United States report.

"The purpose of this Study was to therefore test the hypothesis that PKC epsilon. contributes to ethanol-induced steatosis. Accordingly, the effect of acute ethanol on indices of hepatic steatosis and insulin signaling were determined in PKC epsilon knockout mice and in...

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Source: Gene Therapy Weekly (2009-04-23)

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