Angiogenesis

Data on angiogenesis detailed by researchers at University of California, Medical Department

Published in Gene Therapy Weekly, May 7th, 2009

According to recent research published in the World Journal of Surgery, "Enhanced angiogenesis and perineural invasion are markers of poor prognosis in patients with pancreatic cancer. Systemic therapies for pancreatic cancer have been largely ineffective, and thus improved, targeted therapies are needed."

"Single nucleotide polymorphisms (SNP) are DNA sequence variations that result in vast diversity of disease susceptibility and response to disease. CXCR2 is an important mediator of CXC chemokine-induced angiogenesis and is upregulated in pancreatic cancer. In a preclinical corneal micropocket assay, treatment of pancreatic cancer cell lines that express CXCR2...

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Source: Gene Therapy Weekly (2009-05-07)

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