Gene Therapy

Scientists at Princeton University release new data on gene therapy

Published in Gene Therapy Weekly, May 7th, 2009

According to a study from the United States, "microRNAs play a critically important role in a wide array of biological processes including those implicated in cancer, neuro-degenerative and metabolic disorders, and viral infection. Although we have begun to understand microRNA biogenesis and function, experimental demonstration of their functional effects and the molecular mechanisms by which they function remains a challenge."

"Members of the let-7/miR-98 family play a critical role in cell cycle control with respect to differentiation and tumorigenesis. In this study, we show that exogenous addition of pre-let-7 in primary human fibroblasts results in a decrease in...

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Source: Gene Therapy Weekly (2009-05-07)

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