Colon Cancer

Reports outline colon cancer research from University of Hong Kong

Published in Gene Therapy Weekly, June 4th, 2009

"Four and a half of LIM-only protein 2 (FHL2) is an adaptor protein that can interact with many transcription factors and thus plays a variety of biological functions. Previous studies by our group have demonstrated that suppression of FHL2 was capable of inducing tumor cell differentiation, and inhibiting the growth of experimental gastric and colon cancers," investigators in Hong Kong, People's Republic of China report.

"Therefore, FHL2 appears to function as an oncogene. In order to further explore the mechanisms of how FHL2 is involved in tumorigenesis, we attempted to test whether FHL2 has any direct association with nuclear factor (NF-kappa B), the most important...

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Source: Gene Therapy Weekly (2009-06-04)

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