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Enzyme Research
New enzyme research from University of Alberta described
June 18th, 2009
According to recent research from Edmonton, Canada, "By 1959, Eugene Kennedy and coworkers had outlined most pathways of phospholipid biosynthesis. In the next four decades, the emphasis was on enzymology and regulation of these pathways." "In the last 12 years, several lines of mice with disrupted genes of phospholipid biosynthesis were generated. From this research, we have learned that embryonic lethality occurs in mice that lack choline kinase (CK) alpha, CTP: phosphocholine cytidylyltransferase alpha, CTP: phosphoethanolamine cytidylyltransferase, or phosphatidylserine decarboxylase. Whereas mice that lack CK beta are viable but develop hindlimb muscular dystrophy...
Source: Gene Therapy Weekly (2009-06-18)
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