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Gene Therapy Weekly

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Enzyme Research



Research from University of Nice in the area of enzyme research described



June 18th, 2009

"Extracellular signal-related kinase (ERK) is a well-known kinase taking part in a signal transduction cascade in response to extracellular stimuli. ERK is generally viewed as a kinase that is rapidly and transiently phosphorylated following mitogenic stimulation," scientists writing in the Febs Journal report.

"This activation results in ERK phosphorylating further downstream targets, thus transmitting and amplifying the original stimulus, and ultimately resulting in the onset of cellular proliferation and/or protection against apoptosis. More recently, several groups have identified a strikingly new type of ERK activation that results in cell death. This...


Source: Gene Therapy Weekly (2009-06-18)

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