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Gene Therapy
New gene therapy study findings have been published by scientists at University of Chile
June 18th, 2009
According to recent research from Santiago, Chile, "Augmented expression of cyclooxygenase-2 (COX-2) and enhanced production of prostaglandin E-2 (PGE(2)) are associated with increased tumor cell survival and malignancy. Caveolin-1 is a scaffold protein that has been proposed to function as a tumor suppressor in human cancer cells, although mechanisms underlying this ability remain controversial." "Intriguingly, the possibility that caveolin-1 regulates the expression of COX-2 has not been explored. Here we show that augmented caveolin-1 expression in cells with low basal levels of this protein, such as human colon cancer (HT29, DLD-1), breast cancer (ZR75), and...
Source: Gene Therapy Weekly (2009-06-18)
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