RNA Research
Researchers at Technical University of Munich publish new data on RNA research
Published in Gene Therapy Weekly, June 18th, 2009
"We identified expression of histone methyltransferase enhancer of Zeste, Drosophila, Homolog 2 (EZH2) to be increased in ET. Suppressive activity of EZH2 maintains sternness in normal and malignant cells. Here, we found EWS/FLI1 bound to the EZH2 promoter in vivo, and induced EZH2 expression in ET and mesenchymal stem cells. Down-regulation of EZH2 by RNA interference in ET suppressed oncogenic...
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Source: Gene Therapy Weekly (2009-06-18)
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