Cancer Immunology
Research findings from Shandong University update understanding of cancer immunology
Published in Gene Therapy Weekly, July 2nd, 2009
New research, 'Sodium butyrate upregulates expression of NKG2D ligand MICA/B in HeLa and HepG2 cell lines and increases their susceptibility to NK lysis,' is the subject of a report. "Natural killer (NK) cells are important effectors in the immune response to tumors. A number of cell-surface inhibitory and activating receptors on NK cells tightly regulate their interaction with target cell ligands," researchers in Jinan, People's Republic of China report.
"In particular, the strength of an anti-tumor immune response appears to depend critically on surface levels of one activating receptor, NKG2D. Correspondingly, expression of NKG2D ligands on target cells is a...
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Source: Gene Therapy Weekly (2009-07-02)
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