Gene Therapy
University of Minnesota details research in gene therapy
Published in Gene Therapy Weekly, July 2nd, 2009
A report, 'High-titer lentiviral vectors stimulate fetal calf serum-specific human CD4 T-cell responses: implications in human gene therapy,' is newly published data in Gene Therapy. "Human immunodeficiency virus-1-derived lentiviral vectors have been increasingly used for gene delivery in both pre-clinical and clinical models. Numerous studies have shown that dendritic cells (DC) transduced with concentrated lentiviral vectors can induce primary T-cell responses to viral and tumor antigens," researchers in the United States report.
"In this study, we attempted to generate influenza hemagglutinin-specific CD4 T cells using lentiviral vectors containing the signal...
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Source: Gene Therapy Weekly (2009-07-02)
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