Hepatocellular Cancer

Reports from Jilin University add new data to research in hepatocellular cancer

Published in Gene Therapy Weekly, July 23rd, 2009

According to recent research published in the journal Cell Cycle, "Wnt/beta-catenin signaling pathway and cell cycle play the key roles during the genesis and development of hepatocellular carcinoma (HCC). The cytoplasmic protein beta-catenin is a multifunctional protein and a central molecule in the Wnt signaling pathway."

"Cell cycle is regulated by a a series of regulatory factors. Current researches indicated that expression of cyclin D1 and c-myc decreased after silencing beta-catenin gene in HCC, but it is unclear if other cyclins are affected. To determine the relation, small interference RNA(siRNA) against beta-catenin was transfected into HCC cell line...

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Source: Gene Therapy Weekly (2009-07-23)

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