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Melanoma Cell Biology

New melanoma cell biology research reported from University of Florida, College of Medicine

Published in Gene Therapy Weekly, July 23rd, 2009

Research findings, 'Hematopoietic- and neurologic-expressed sequence 1 (Hn1) depletion in B16.F10 melanoma cells promotes a differentiated phenotype that includes increased melanogenesis and cell cycle arrest,' are discussed in a new report. According to a study from the United States, "The Hematopoietic-and neurologic-expressed sequence 1 (Hn1) gene encodes a small protein that is highly conserved among species. Hn1 expression is upregulated in regenerating neural tissues, including the axotomized adult rodent facial motor nerve and dedifferentiating retinal pigment epithelial cells of the Japanese newt."

"It is also expressed in numerous tissues during embryonic...

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