Antisense Technology
Reports summarize antisense technology research from E. Gogvadze and co-authors
Published in Gene Therapy Weekly, July 23rd, 2009
"Many phenotypic differences exist between Homo sapiens and its closest relatives, chimpanzees, and these differences can arise as a result of variations in the regulation of certain genes common to these closely related species. Human-specific endogenous retroviruses (HERVs) and their solitary long terminal repeats (LTRs) are probable candidates for such a role due to the presence of regulatory elements, such as enhancers, promoters, splice sites, and polyadenylation signals," investigators in Russia report.
"In this study we show for the first time that HERVs can participate in the specific antisense regulation of human gene expression owing to their LTR promoter...
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Source: Gene Therapy Weekly (2009-07-23)
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