Adenovirus

Studies from B. Xiao et al have provided new data on adenovirus

Published in Gene Therapy Weekly, August 6th, 2009

According to recent research from Yangling, People's Republic of China, "For producing a large quantity of human nerve growth factor beta (hNGF-beta), the recombinant adenovirus containing an expression cassette of hNGF-beta complementary DNA gene was constructed and then instilled directly into goats' mammary glands. The recombinant hNGF-beta was detected in the milk."

"The maximal expression level of recombinant hNGF-beta in the milk reached 196.8 mg/l. The biological activity of the recombinant hNGF-beta, compared with the commercial hNGF-beta, was tested using PC12 cells," wrote B. Xiao and colleagues.

The researchers concluded: "The results...

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Source: Gene Therapy Weekly (2009-08-06)

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